4-Hydroxy-N-methyl-N-isopropyltryptamine (also known as 4-HO-MiPT, and Miprocin) is a synthetic psychedelic substance of the tryptamine chemical class that produces effects similar to psilocin (the active component in psilocybin mushrooms) when administered. It is part of a series of psychedelic substituted tryptamines such as 4-AcO-DMT, 4-HO-MET, 4-HO-DiPT that are considered to produce variations of the core psychedelic effects typified by psilocin.

This substance is relatively uncommon and has only a short history of human use. Alexander Shulgin evaluated its activity in humans in 1979, describing a trial of 12mg as a richly insightful and highly erotic experience.[1] A description of it is included in Shulgin’s 1997 book TiHKAL.[2] Shulgin’s trials and other anecdotal reports suggest that it is similar in activity to psilocin, the active component in psilocybin mushrooms.

Very little data exists about the pharmacological properties, metabolism, and toxicity of it in humans. As with psilocin, there have been no reported deaths from it use despite the existence of reports of people taking doses which far exceeds the active dose. This suggests that it is well-tolerated physiologically.[citation needed]

Today, it is either used recreationally or as an entheogenic substance and is typically distributed as a grey-area research chemical by online vendors. After some time spent exclusively on the online market, there is evidence that suggests it is becoming increasingly popular on the streets, where prefilled capsules containing it have been found being sold as “shroom pills.

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